Objectives: the Cochrane Statistical Methods Group has developed a series of workshops addressing statistical guidelines as formulated in the Cochrane Handbook for Systematic Reviews of Interventions. Time-to-event data, such as time to death or time to first seizure, are commonly used outcomes in medical research to summarize the length of time taken for a particular event of interest to occur. This workshop will discuss how to undertake a meta-analysis of time-to-event data.
Description: methods for analysis of time-to-event data need to account for both the time to event and any related but unobserved events. Meta-analysis of time-to-event outcomes can be undertaken using data extracted from trial reports using a variety of different methods including an alternative, more resource-intensive approach, which involves a re-analysis of individual participant data.